Fortune’s 2025 list of the 100 Most Powerful Women in Business highlights top female leaders driving innovation and transformation across global industries. Topping the list for the fifth time is Mary Barra, GM’s CEO, recognized for her leadership in electric vehicle advancement and navigating complex industry challenges. The list also features influential leaders like Accenture’s Julie Sweet and Citigroup’s Jane Fraser, showcasing a diverse and international group reshaping the future of business.