Zoe Saldaña has become the highest-grossing actor of all time at the global box office, with her films’ combined earnings surpassing $15.4 billion, dethroning Scarlett Johansson after the massive success of Avatar: Fire and Ash. Her career includes key roles in some of the biggest franchise films ever, including the Avatar and Avengers series, highlighting how relentless blockbuster presence can redefine Hollywood milestones.